Distinguishing phenotypes of childhood wheeze and cough using latent class analysis
نویسندگان
چکیده
منابع مشابه
Distinguishing phenotypes of childhood wheeze and cough using latent class analysis.
Airway disease in childhood comprises a heterogeneous group of disorders. Attempts to distinguish different phenotypes have generally considered few disease dimensions. The present study examines phenotypes of childhood wheeze and chronic cough, by fitting a statistical model to data representing multiple disease dimensions. From a population-based, longitudinal cohort study of 1,650 preschool ...
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BACKGROUND To advance asthma cohort research, we need a method that can use longitudinal data, including when collected at irregular intervals, to model multiple phenotypes of wheeze and identify both time-invariant (eg, sex) and time-varying (eg, environmental exposure) risk factors. OBJECTIVE To demonstrate the use of latent class growth analysis (LCGA) in defining phenotypes of wheeze and ...
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G. Lorillon*, M. Robin, V. Meignin, P. Ribaud, B. Lescoeur, D. Gossot, G. Socié, A. Tazi* and A. Bergeron* *Service de Pneumologie, Service d’Hématologie-Greffe, Service de Pathologie, Hôpital Saint-Louis, Université Paris 7, UFR Denis Diderot; Assistance Publique-Hôpitaux de Paris, Service d’Hématologie Pédiatrique, Hôpital Robert Debré, Université Paris 7, UFR Denis Diderot; Assistance Publiq...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2008
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00153507